Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be completely remedied with standard nutrition support, resulting in diminishing functionality. It may be masked by excess weight, obesity, edema, or tumor mass. Anorexia signifies a diminished appetite, often observed in cancer patients, although its precise prevalence remains uncertain.
When cachexia primarily stems from reduced intake, it is termed cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, lipolysis, and decreased food intake, distinguishing it from simple cachexia.
Some researchers suggest that cannabis from Cheapweed.io Canada could enhance appetite and alleviate nausea in cancer patients.
Table of Contents
Key Takeaways:
- THC capsules from Cheapweed.io Canada may assist cancer patients in consuming more and feeling less ill, thereby enhancing their quality of life.
- Studies indicate that cannabis influences brain cells responsible for hunger, potentially aiding appetite issues in cancer patients and others.
- THC capsules provide accurate, convenient, private, and long-lasting options for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia refers to a condition marked by significant weight loss due to muscle and fat depletion, commonly seen in patients with advanced illnesses such as heart failure, HIV/AIDS, COPD, kidney failure, and especially cancer.
This condition often accompanies anorexia, which results in a reduced appetite leading to at least a 5% decrease in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS).
Hospitalized cancer patients frequently exhibit poor dietary intake, with up to half being malnourished or at risk. Cachexia not only reduces patients’ quality of life but also hinders treatment and can hasten the end of life. Its prevalence escalates significantly as death approaches, with cachexia identified as the primary cause of death in over 20% of cases.
Despite its common occurrence, CACS frequently goes unnoticed and untreated in clinical environments due to the lack of clear definitions, diagnostic criteria, classification systems, and approved therapies. Clinicians evaluate a patient’s nutritional status using various metrics such as body weight, skin fold thickness, and mid-arm circumference, often relying on body weight, typically using inappropriate reference weights.
Treatment
The most apparent method to tackle anorexia is to enhance nutrition; however, evidence supporting its efficacy is limited. For cancer patients, nutritional care includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
Nevertheless, success rates vary based on the type and stage of cancer.
Pharmacological Approaches
Currently, there are no confirmed medications for treating Cancer Anorexia-Cachexia Syndrome (CACS), but some drugs are utilized off-label or are in clinical trials. These medications can be categorized into four groups based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is used separately due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid may enhance the lives of cancer patients and pave the way for future treatments, offering hope for cachexia patients who suffer from appetite loss and malnutrition. It provides relief without intoxicating effects, making it a possible solution for these individuals.
Various cannabis formulations with differing effects are available, including inhaled THC for rapid onset and short-lived effects, as well as orally ingested THC for slower absorption and longer-lasting effects. Sublingual administration offers a quick onset lasting 2 to 4 hours.
Clinical Trial
A study conducted by researchers from Israel and the United States assessed how cannabis pills influence CACS in advanced cancer patients. This finding significantly impacts the treatment of appetite disorders faced by cancer patients and individuals with anorexia, as well as potentially obesity.
Methods
The study utilized cannabis capsules containing two types of oil-based compounds. Participants were treated with 10 mg doses twice daily for six months, comprising 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants experienced any side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). During each doctor’s visit, participants were weighed, with the primary objective being for them to gain at least 10% more weight than their initial weight.
Results
Out of 24 patients who consented to participate, 17 began treatment with cannabis capsules. However, only 11 continued taking the capsules for more than two weeks. By the study’s conclusion, 3 out of 6 patients who completed the treatment achieved the main goal of gaining at least 10% more weight. The weight of the remaining three patients remained unchanged.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Patients reported improved appetite and mood, along with reduced pain and fatigue.
Despite various challenges, this preliminary study indicated a 10% or greater weight gain in 3 out of 17 patients (17.6%) consuming daily doses of 5 mg without significant side effects. These results support the need for a larger, more controlled study on cannabis capsules in patients with CACS.
Cannabis Capsules
If you enjoy edibles, cannabis flower, or classic pre-rolls, exploring new ways to enjoy cannabis is always thrilling.
THC capsules from Cheapweed.io Canada represent one of the latest innovations in the cannabis market. These capsules contain a precise dose of THC made from a concentrated cannabis extract and a neutral oil, akin to cannabis tinctures in capsule form (also referred to as cannabis oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract is obtained from the cannabis plant using a method selected by the manufacturer for extraction. THC capsules are rich in THC, while some may exclusively contain CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble, thus it is suspended in an oil for optimal absorption by the body. Common oils used include medium-chain triglycerides (MCT oils), which aid in digestion and absorption.
Benefits
Patients using medical marijuana and recreational users can take advantage of cannabis capsules. They provide:
- Convenience: Taking a cannabis capsule is as simple as any other oral supplement. Just swallow it with water, no fuss.
- Precision Dosage: For medical users, exact control over cannabinoid intake is essential for achieving desired effects. With THC capsules, each dose is measured, eliminating uncertainty.
- Smoke-Free Option: Many individuals prefer to avoid smoking or vaping due to personal choice or health concerns. THC capsules present a smoke-free alternative suitable for those with respiratory issues.
- Longer Effects: Capsules often deliver longer-lasting effects compared to smoking or vaping, making them ideal for prolonged relief from symptoms over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
| Aspect | Cannabis Capsules | Other Forms of Medicinal Cannabis |
| Dosing | Precise dosing with each capsule | Dosing may vary depending on the method of consumption (e.g., smoking, vaping, edibles) |
| Consumption | Oral ingestion | Smoking, vaping, edibles, tinctures |
| Effects | Longer-lasting, gradual onset | Immediate onset, shorter duration |
| Effects on Appetite Stimulation | Gradual stimulation | Immediate stimulation |
Place a Medical Cannabis Delivery Order Conveniently
With the rising demand for dependable cannabis delivery services, online dispensaries offer a smooth solution. From same-day cannabis delivery to high-quality cannabis products, these dispensaries provide a broad range of options to meet every preference and requirement.
If you’re searching for cannabis flower, pre-rolls, edibles, or vape pens, you can easily explore Cheapweed.io Canada’s top marijuana products derived from the highest quality cannabis plants. Shop for your preferred THC products from the comfort of your home.
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Frequently Asked Questions
What are the different types of capsules?
Another benefit of cannabis pills/capsules is their versatility – formulators can create various capsule types for consumers to select from, allowing you to find capsules that suit your personal preference.
- 1:1 Capsules: These capsules deliver an equal ratio of THC to CBD in each dose. They can be made with sativa or indica strains and come in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules provide a ratio of 3 parts CBD to 1 part THC in each dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, made from different sativa or indica strains to offer specific effects.
- CBD Capsules: These contain only CBD, without THC, so they do not produce mind-altering effects. They are designed for individuals seeking the benefits of CBD alone.
How do capsules interact with your body?
- The capsule’s outer shell disintegrates in your digestive tract once consumed.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) are metabolized in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take about 90 minutes to begin exhibiting effects. The effects can last from 5 to 12 hours, gradually diminishing in intensity. Compared to inhaled cannabis, capsule effects tend to last twice as long on average.
However, experiences may vary based on factors such as age, medications, personal cannabis tolerance, and cannabinoid composition. Some users also report different effects depending on specific cannabinoids present, potentially due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, locate a trustworthy delivery service online that offers premium quality cannabis products. After selecting your items, choose “order cannabis delivery,” and a delivery driver will securely bring your order. Ensure the service is reputable for a seamless purchasing experience.
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